Metformin’s mysterious metal effect could explain its big health benefits

Sep 3, 2025 - 17:00
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Metformin’s mysterious metal effect could explain its big health benefits
Metformin, the world’s most widely used diabetes drug, has long been recognized for its surprising range of benefits beyond lowering blood sugar, from reducing inflammation to lowering cancer risk. Yet its exact mechanism has remained unclear for decades. Now, researchers at Kobe University have uncovered the first clinical evidence that the drug alters levels of key metals in the blood.

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