From cursed tomb fungus to cancer cure: Aspergillus flavus yields potent new drug
In a remarkable twist of science, researchers have transformed a fungus long associated with death into a potential weapon against cancer. Found in tombs like that of King Tut, Aspergillus flavus was once feared for its deadly spores. Now, scientists at Penn and several partner institutions have extracted a new class of molecules from it—called asperigimycins—that show powerful effects against leukemia cells. These compounds, part of a rare group known as fungal RiPPs, were bioengineered for potency and appear to disrupt cancer cell division with high specificity.
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